Abstract
Objective
To test the hypothesis that homoeopathy is a placebo by examining its effect in patients with allergic rhinitis and so contest the evidence from three previous trials in this series.
Design
Randomised, double blind, placebo controlled, parallel group, multicentre study.
Setting
Four general practices and a hospital ear, nose, and throat outpatient department.
Participants
51 patients with perennial allergic rhinitis.
Intervention
Random assignment to an oral 30c homoeopathic preparation of principal inhalant allergen or to placebo.
Main outcome measures
Changes from baseline in nasal inspiratory peak flow and symptom visual analogue scale score over third and fourth weeks after randomisation.
Results
Fifty patients completed the study. The homoeopathy group had a significant objective improvement in nasal airflow compared with the placebo group (mean difference 19.8 l/min, 95% confidence interval 10.4 to 29.1, P=0.0001). Both groups reported improvement in symptoms, with patients taking homoeopathy reporting more improvement in all but one of the centres, which had more patients with aggravations. On average no significant difference between the groups was seen on visual analogue scale scores. Initial aggravations of rhinitis symptoms were more common with homoeopathy than placebo (7 (30%) v 2 (7%), P=0.04). Addition of these results to those of three previous trials (n=253) showed a mean symptom reduction on visual analogue scores of 28% (10.9 mm) for homoeopathy compared with 3% (1.1 mm) for placebo (95% confidence interval 4.2 to 15.4, P=0.0007).
Conclusion
The objective results reinforce earlier evidence that homoeopathic dilutions differ from placebo
Med andra ord:
Studiens resultat stärker, det man redan visste, nämligen att homeopatisk medicin är bättre än placebo
Läs hela studien: >>>
Karl Otto Aly: Är homeopati verkligen bara placebo?
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